NIH-funded research U01 cooperative agreement

Improving understanding and treatment of lower urinary tract symptoms

Official title: Advancing the Measurement and Classification of Lower Urinary Tract Dysfunction

Funded at Duke University · NIH-11089075 · Data updated 2026-11-12

This study is looking at different types of lower urinary tract symptoms (LUTS) that many adults experience, with the goal of grouping patients based on their specific symptoms to find better ways to treat them and improve their quality of life.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionDuke University
NIH-funded
Lab location1 site (Durham, United States)
Project startSeptember 1, 2023
Project endAugust 31, 2025
Funding year2024
Award (this year)$140,000
NIH project number3U01DK097780-10S1
Project IDNIH-11089075 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults aged 21 and older who experience lower urinary tract symptoms.

Less likely to help

Patients with urinary tract symptoms caused by non-functional disorders or those outside the age range may not benefit from this research.

What this research studies

This research focuses on lower urinary tract symptoms (LUTS), which affect a significant portion of adults and can severely impact quality of life. The project aims to categorize patients with LUTS into distinct subgroups to better understand the underlying causes and improve treatment options. By integrating self-reported symptoms, clinical exams, and laboratory results, the research seeks to develop comprehensive measurement tools that can enhance treatment efficacy. The goal is to address the heterogeneity of LUTS and provide more personalized care for patients.

Why it matters

Potential benefit: If successful, this research could lead to more effective and tailored treatments for patients suffering from lower urinary tract symptoms.

How similar studies have gone: Previous research has shown promise in categorizing similar patient populations, indicating that this approach could yield beneficial results.

Where this research is happening

  • Duke University
    Durham, United States
    Active

Researchers

  • Principal investigator: Amundsen, Cindy — Duke University
  • Study coordinator: Amundsen, Cindy

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.