Improving understanding and treatment of gastroparesis at the University of Louisville
U of L Clinical Center to Investigate the Pathogenesis, Etiology, and Treatment of Gastroparesis through the NIDDK Gastroparesis Consortium
This consortium effort brings clinical experts together to learn more about what causes gastroparesis and to improve care for people with delayed stomach emptying, nausea, vomiting, and related symptoms.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Louisville NIH-funded |
| Lab location | 1 site (Louisville, United States) |
| Project ID | NIH-11158674 on NIH RePORTER |
What this research studies
If you join, you would work with specialists who follow people with gastroparesis over time to better understand symptoms, test results, and long‑term outcomes. You may have standardized symptom surveys, stomach emptying tests, and other clinical measurements, and you might be asked to give biological samples for research. The program coordinates multiple centers to compare patients by cause, severity, and test findings and may offer access to clinical treatment options or trials. The goal is to make care less trial‑and‑error and to develop clearer, more effective treatment approaches.
Who could benefit from this research
Good fit: Adults (especially women) with a diagnosis of gastroparesis or persistent symptoms such as chronic nausea, vomiting, early satiety, or documented delayed gastric emptying would be the main candidates.
Not a fit: People without gastroparesis or with unrelated gastrointestinal conditions, or those unwilling to undergo testing or follow‑up visits, are unlikely to benefit from participation.
Why it matters
Potential benefit: Better understanding of causes and disease course could lead to more effective, targeted treatments and clearer guidance on nutrition and long‑term outcomes.
How similar studies have performed: Previous work from the Gastroparesis Clinical Research Consortium has improved knowledge and led to some treatment advances, but many therapies remain only partially effective and more study is needed.
Where this research is happening
Louisville, United States
- University of Louisville — Louisville, United States (Active)
Researchers
- Principal investigator: Abell, Thomas Lyman — University of Louisville
- Study coordinator: Abell, Thomas Lyman
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.