Improving understanding and assessment of lower urinary tract symptoms

LURN II: Enhanced Characterization of Patients with LUTS Using Biopsychosocial Approaches

NIH-funded research University of Chicago · NIH-11143545

This study is all about getting a better grasp on lower urinary tract symptoms (LUTS) by creating better questionnaires with help from patients and doctors, while also looking at blood tests and how the urinary system works in both men and women, so we can understand how LUTS affects everyday life.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-11143545 on NIH RePORTER

What this research studies

This research focuses on enhancing the understanding of lower urinary tract symptoms (LUTS) through a patient-centered approach. It aims to improve self-report measurements of LUTS by developing high-quality questionnaire items based on input from patients and healthcare professionals. The study will also explore biomarkers in blood plasma and assess the functional characteristics of the lower urinary tract in both men and women. By refining these assessments, the research seeks to provide a more comprehensive understanding of LUTS and its impact on daily life.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals experiencing lower urinary tract symptoms, regardless of severity.

Not a fit: Patients without any urinary tract symptoms or those with unrelated conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better diagnosis and treatment options for patients suffering from lower urinary tract symptoms.

How similar studies have performed: Previous research in the field of LUTS has shown promise in improving patient assessments and outcomes, indicating that this approach may build on established findings.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.