Improving ultrasound treatment for blood clots using microbubbles
A Numerical Platform for Microbubble Enhanced Sonothrombolysis
This study is looking at how to make ultrasound treatments for blood clots safer and more effective by using tiny bubbles, which could help doctors remove clots more easily without needing high-intensity ultrasound, making it better for patients like you.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dynaflow, INC. NIH-funded |
| Lab location | 1 site (Jessup, United States) |
| Project ID | NIH-10821632 on NIH RePORTER |
What this research studies
This research focuses on enhancing non-invasive ultrasound treatments for thrombosis, a major cause of death and disability. By incorporating microbubbles, the study aims to improve the effectiveness of clot removal at lower ultrasound intensities. The project will develop a numerical platform to better understand the complex interactions between microbubbles and blood clots, allowing for accurate predictions of clot lysis rates under various conditions. This innovative approach seeks to overcome existing challenges in the biophysics of thrombolysis, potentially leading to safer and more effective treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk of thrombosis or those who have experienced blood clots and are seeking alternative treatment options.
Not a fit: Patients with conditions that do not involve thrombosis or those who are not candidates for ultrasound treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer, more effective non-invasive treatments for blood clots, reducing the risks associated with conventional therapies.
How similar studies have performed: Previous research has shown promise in using ultrasound and microbubbles for thrombolysis, indicating that this approach has potential for success.
Where this research is happening
Jessup, United States
- Dynaflow, INC. — Jessup, United States (Active)
Researchers
- Principal investigator: Ma, Jingsen — Dynaflow, INC.
- Study coordinator: Ma, Jingsen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.