Improving ultrasound treatment for blood clots using microbubbles
Official title: A Numerical Platform for Microbubble Enhanced Sonothrombolysis
Funded at Dynaflow, INC. · NIH-10821632 · Data updated 2026-11-12
This study is looking at how to make ultrasound treatments for blood clots safer and more effective by using tiny bubbles, which could help doctors remove clots more easily without needing high-intensity ultrasound, making it better for patients like you.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dynaflow, INC. NIH-funded |
| Lab location | 1 site (Jessup, United States) |
| Project start | September 17, 2024 |
| Project end | September 16, 2025 |
| Funding year | 2024 |
| Award (this year) | $281,956 |
| NIH project number | 1R43HL172528-01 |
| Project ID | NIH-10821632 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at risk of thrombosis or those who have experienced blood clots and are seeking alternative treatment options.
✕Less likely to help
Patients with conditions that do not involve thrombosis or those who are not candidates for ultrasound treatments may not benefit from this research.
What this research studies
This research focuses on enhancing non-invasive ultrasound treatments for thrombosis, a major cause of death and disability. By incorporating microbubbles, the study aims to improve the effectiveness of clot removal at lower ultrasound intensities. The project will develop a numerical platform to better understand the complex interactions between microbubbles and blood clots, allowing for accurate predictions of clot lysis rates under various conditions. This innovative approach seeks to overcome existing challenges in the biophysics of thrombolysis, potentially leading to safer and more effective treatments.
Why it matters
Potential benefit: If successful, this research could lead to safer, more effective non-invasive treatments for blood clots, reducing the risks associated with conventional therapies.
How similar studies have gone: Previous research has shown promise in using ultrasound and microbubbles for thrombolysis, indicating that this approach has potential for success.
Where this research is happening
-
Dynaflow, INC.
Jessup, United States Active
Researchers
- Principal investigator: Ma, Jingsen — Dynaflow, INC.
- Study coordinator: Ma, Jingsen
Related research
Other NIH-funded projects on the same topics.
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A platform to enhance ultrasound treatment for blood clots
This study is working on a new tool to help doctors find the best ways to use special sound waves and tiny bubbles to treat blood clots, making sure the treatment is just right for each patient.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.