Improving ultrasound surgeries for brain diseases using a new iron-based medium

Iron Based Coupling Media (IBCM) for MRI-guided Transcranial Ultrasound Surgeries

['FUNDING_R01'] · BRIGHAM YOUNG UNIVERSITY · NIH-10894093

This study is looking at a new way to make a noninvasive brain treatment more accurate for people with conditions like Alzheimer's, brain cancer, and movement disorders by using a special iron-based material, which could help improve their treatment results.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorBRIGHAM YOUNG UNIVERSITY (nih funded)
Locations1 site (PROVO, UNITED STATES)
Trial IDNIH-10894093 on ClinicalTrials.gov

What this research studies

This research focuses on enhancing the effectiveness of transcranial magnetic resonance guided focused ultrasound surgery (tMRgFUS) for treating various neurological conditions. By developing a new iron-based coupling medium, the study aims to improve the accuracy of MRI guidance during these noninvasive procedures. This could lead to better outcomes for patients undergoing treatment for conditions like Alzheimer's disease, brain cancer, and movement disorders. The approach seeks to eliminate errors caused by traditional coupling media that can hinder the precision of the ultrasound treatment.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals suffering from neurological diseases such as Alzheimer's, brain cancer, or movement disorders who may benefit from ultrasound surgery.

Not a fit: Patients with conditions that do not require or are not suitable for ultrasound surgery may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve the efficacy of noninvasive brain surgeries, leading to better patient outcomes and reduced complications.

How similar studies have performed: While the use of ultrasound surgery is established, the specific application of an iron-based coupling medium is a novel approach that has not been extensively tested in prior research.

Where this research is happening

PROVO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.