Improving ultrasound imaging for noninvasive kidney tumor treatment
Official title: Imaging Feedback for Histotripsy Renal Tumor Ablation
Funded at University of Chicago · NIH-11123993 · Data updated 2026-11-12
This study is working on a new way to use ultrasound imaging to help doctors better monitor a noninvasive treatment for kidney tumors, making it easier and more effective for patients who can't have traditional surgery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | July 1, 2024 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $526,936 |
| NIH project number | 5R01EB035230-02 |
| Project ID | NIH-11123993 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with renal cell carcinoma who may benefit from noninvasive treatment options.
✕Less likely to help
Patients with renal cell carcinoma who are eligible for traditional surgical interventions may not receive direct benefits from this research.
What this research studies
This research focuses on enhancing ultrasound imaging techniques to improve the monitoring of a noninvasive treatment called histotripsy for kidney tumors. Histotripsy uses focused ultrasound to destroy cancerous tissue through bubble activity, but current imaging methods struggle to accurately visualize these bubbles, especially in complex tumors. By developing a new, ultrafast imaging technique, the research aims to provide real-time feedback during treatment, ensuring better outcomes for patients with renal cell carcinoma. This approach could help automate the treatment process and make it more effective for patients who may not qualify for traditional surgery.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer treatment options for patients with kidney tumors, particularly those who are not candidates for surgery.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for similar noninvasive treatments, indicating potential for success in this novel approach.
Where this research is happening
-
University of Chicago
Chicago, United States Active
Researchers
- Principal investigator: Bader, Kenneth B. — University of Chicago
- Study coordinator: Bader, Kenneth B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.