Improving ultrasound imaging for noninvasive kidney tumor treatment

Imaging Feedback for Histotripsy Renal Tumor Ablation

NIH-funded research University of Chicago · NIH-11123993

This study is working on a new way to use ultrasound imaging to help doctors better monitor a noninvasive treatment for kidney tumors, making it easier and more effective for patients who can't have traditional surgery.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-11123993 on NIH RePORTER

What this research studies

This research focuses on enhancing ultrasound imaging techniques to improve the monitoring of a noninvasive treatment called histotripsy for kidney tumors. Histotripsy uses focused ultrasound to destroy cancerous tissue through bubble activity, but current imaging methods struggle to accurately visualize these bubbles, especially in complex tumors. By developing a new, ultrafast imaging technique, the research aims to provide real-time feedback during treatment, ensuring better outcomes for patients with renal cell carcinoma. This approach could help automate the treatment process and make it more effective for patients who may not qualify for traditional surgery.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients diagnosed with renal cell carcinoma who may benefit from noninvasive treatment options.

Not a fit: Patients with renal cell carcinoma who are eligible for traditional surgical interventions may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and safer treatment options for patients with kidney tumors, particularly those who are not candidates for surgery.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for similar noninvasive treatments, indicating potential for success in this novel approach.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancers
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.