Improving ultrasound imaging for breast cancer treatment monitoring

Use of Radiological Clips for Improving Quantitative Ultrasound Imaging

NIH-funded research University of Illinois at Urbana-Champaign · NIH-10832466

This study is looking at how special clips made of titanium or gold can help doctors better see and remove tumors in patients with advanced breast cancer who are getting chemotherapy, making it easier to track how well the treatment is working.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Illinois at Urbana-Champaign NIH-funded
Lab location1 site (Champaign, United States)
Project IDNIH-10832466 on NIH RePORTER

What this research studies

This research focuses on enhancing quantitative ultrasound (QUS) imaging techniques by using radiological clips made of titanium or gold. These clips are placed in tumors to help surgeons accurately locate and remove cancerous tissue, particularly in patients with locally advanced breast cancer undergoing chemotherapy. The study aims to improve the accuracy of QUS in detecting tumor responses to treatment by incorporating a novel calibration procedure that utilizes these clips. By monitoring therapy response, this approach could provide valuable insights into the effectiveness of treatment early on.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients with locally advanced breast cancer who are undergoing neoadjuvant chemotherapy.

Not a fit: Patients with early-stage breast cancer or those not receiving chemotherapy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate monitoring of breast cancer treatment responses, allowing for timely adjustments in therapy.

How similar studies have performed: Previous studies have shown promise in using quantitative ultrasound techniques for monitoring tumor responses, indicating that this approach may build on established methods.

Where this research is happening

Champaign, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Breast CancerCancersneoplasm/cancer
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.