Improving tumor imaging accuracy with micro-capsules
Official title: IMAT-ITCR Collaboration: Multiplexed Spatial Data calibration and analysis using micro-capsules
Funded at Harvard Medical School · NIH-11136707 · Data updated 2026-11-12
This study is working on improving the way we look at tumors by making sure the images we get are more accurate and consistent, which will help doctors better understand and compare tumor environments across different labs.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard Medical School NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 12, 2023 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $84,750 |
| NIH project number | 3U01CA284207-02S1 |
| Project ID | NIH-11136707 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients undergoing tumor profiling or imaging for cancer diagnosis and treatment.
✕Less likely to help
Patients with non-cancerous conditions or those not requiring tumor imaging may not receive any benefit from this research.
What this research studies
This research focuses on enhancing the accuracy of highly multiplexed imaging methods used to study tumor microenvironments. By developing reliable calibration standards using micro-capsule technology, the project aims to reduce variability in staining intensity that affects imaging results. The approach involves creating software algorithms that utilize these standards for data normalization, which is crucial for comparing results across different laboratories. This work is essential for advancing clinical workflows and improving the reliability of tumor profiling methods.
Why it matters
Potential benefit: If successful, this research could lead to more accurate tumor imaging, improving diagnosis and treatment strategies for cancer patients.
How similar studies have gone: Previous research has shown promise in using calibration standards to improve imaging techniques, indicating that this approach could be effective.
Where this research is happening
-
Harvard Medical School
Boston, United States Active
Researchers
- Principal investigator: Pfister, Hanspeter — Harvard Medical School
- Study coordinator: Pfister, Hanspeter
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.