Improving tumor imaging accuracy with micro-capsules
IMAT-ITCR Collaboration: Multiplexed Spatial Data calibration and analysis using micro-capsules
This study is working on improving the way we look at tumors by making sure the images we get are more accurate and consistent, which will help doctors better understand and compare tumor environments across different labs.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard Medical School NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11136707 on NIH RePORTER |
What this research studies
This research focuses on enhancing the accuracy of highly multiplexed imaging methods used to study tumor microenvironments. By developing reliable calibration standards using micro-capsule technology, the project aims to reduce variability in staining intensity that affects imaging results. The approach involves creating software algorithms that utilize these standards for data normalization, which is crucial for comparing results across different laboratories. This work is essential for advancing clinical workflows and improving the reliability of tumor profiling methods.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients undergoing tumor profiling or imaging for cancer diagnosis and treatment.
Not a fit: Patients with non-cancerous conditions or those not requiring tumor imaging may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate tumor imaging, improving diagnosis and treatment strategies for cancer patients.
How similar studies have performed: Previous research has shown promise in using calibration standards to improve imaging techniques, indicating that this approach could be effective.
Where this research is happening
Boston, United States
- Harvard Medical School — Boston, United States (Active)
Researchers
- Principal investigator: Pfister, Hanspeter — Harvard Medical School
- Study coordinator: Pfister, Hanspeter
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.