Improving tuberculosis prevention for people with HIV in South Africa
Official title: New pathways to prevention from community TB screening in South Africa
Funded at University of Washington · NIH-10928785 · Data updated 2026-11-12
This study is all about finding better ways to help people living with HIV and those at high risk for tuberculosis in South Africa get the preventive treatment they need, making it easier for them to stick with it and complete their therapy.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | September 13, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $168,574 |
| NIH project number | 5R21AI179276-02 |
| Project ID | NIH-10928785 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals over 21 years old who are living with HIV or are at high risk for tuberculosis.
✕Less likely to help
Patients who are not living with HIV or do not fall into the high-risk categories for tuberculosis may not benefit from this research.
What this research studies
This research focuses on enhancing access to tuberculosis preventive therapy (TPT) for individuals living with HIV and those at high risk for TB in South Africa. It aims to identify and implement new, patient-friendly models of TPT delivery that can increase adherence and completion rates. By leveraging community-based care and innovative treatment approaches, the project seeks to bridge the gap between recommended and actual TPT usage, especially in the context of challenges posed by the COVID-19 pandemic.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of tuberculosis among people living with HIV, improving their overall health outcomes.
How similar studies have gone: Previous research has shown success in community-based models for delivering HIV preventive care, indicating potential for similar success in TPT delivery.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Shapiro, Adrienne E — University of Washington
- Study coordinator: Shapiro, Adrienne E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.