Improving tuberculosis prevention for people with HIV in South Africa

New pathways to prevention from community TB screening in South Africa

NIH-funded research University of Washington · NIH-10928785

This study is all about finding better ways to help people living with HIV and those at high risk for tuberculosis in South Africa get the preventive treatment they need, making it easier for them to stick with it and complete their therapy.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Washington NIH-funded
Lab location1 site (Seattle, United States)
Project IDNIH-10928785 on NIH RePORTER

What this research studies

This research focuses on enhancing access to tuberculosis preventive therapy (TPT) for individuals living with HIV and those at high risk for TB in South Africa. It aims to identify and implement new, patient-friendly models of TPT delivery that can increase adherence and completion rates. By leveraging community-based care and innovative treatment approaches, the project seeks to bridge the gap between recommended and actual TPT usage, especially in the context of challenges posed by the COVID-19 pandemic.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals over 21 years old who are living with HIV or are at high risk for tuberculosis.

Not a fit: Patients who are not living with HIV or do not fall into the high-risk categories for tuberculosis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the incidence of tuberculosis among people living with HIV, improving their overall health outcomes.

How similar studies have performed: Previous research has shown success in community-based models for delivering HIV preventive care, indicating potential for similar success in TPT delivery.

Where this research is happening

Seattle, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.