Improving tuberculosis diagnosis for people with HIV in clinics
Novel clinic-based TB diagnostics and testing algorithms for persons with HIV
This study is working on a new urine test to help doctors quickly and accurately diagnose tuberculosis in people living with HIV in sub-Saharan Africa, so they can get the treatment they need faster without having to send samples to distant labs.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10582608 on NIH RePORTER |
What this research studies
This research focuses on enhancing the diagnosis of tuberculosis (TB) in individuals living with HIV, particularly in sub-Saharan Africa. It aims to develop and implement a new urine-based test that can be used directly in clinics, eliminating the need for lengthy specimen transport to centralized labs. By creating a clinical algorithm to identify patients who need TB testing, the study seeks to improve the speed and accuracy of diagnoses, ultimately leading to timely treatment. The research will evaluate the effectiveness of this new testing method in real-world clinical settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are HIV-infected individuals seeking care at clinics in sub-Saharan Africa.
Not a fit: Patients who are not HIV-infected or those who do not have access to clinics in the targeted regions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce TB-related mortality among people with HIV by enabling faster and more accurate diagnoses.
How similar studies have performed: Previous research has shown promise with point-of-care testing in hospital settings, but this approach in outpatient clinics is novel and untested.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Shapiro, Adrienne E — University of Washington
- Study coordinator: Shapiro, Adrienne E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.