Improving tremor control for patients with severe essential tremor using advanced brain stimulation techniques
Dual Lead Thalamic DBR-DBS Interface for Closed Loop Control of Severe Essential Tremor
This study is testing a new way to help people with severe essential tremor by using a special device that stimulates two areas of the brain at once, aiming to better control tremors and reduce side effects, especially for those who haven't found relief with regular treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-11061909 on NIH RePORTER |
What this research studies
This research investigates a new approach to treating severe essential tremor (ET) by using a dual lead deep brain stimulation (DBS) system. The study aims to replace existing single lead systems with a dual lead system that targets specific areas of the brain to enhance tremor control while minimizing side effects. Additionally, the research will explore the use of deep brain recording (DBR) to monitor brain activity and adjust stimulation in real-time, providing personalized treatment for patients. By focusing on patients who have not responded well to standard treatments, this study seeks to improve their quality of life significantly.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with severe essential tremor who have not achieved satisfactory control with standard deep brain stimulation therapies.
Not a fit: Patients with mild essential tremor or those who have not yet undergone DBS may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for patients suffering from severe essential tremor.
How similar studies have performed: Previous research has shown promise in using advanced DBS techniques for tremor control, indicating that this approach may lead to significant advancements in treatment.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Oweiss, Karim G — University of Florida
- Study coordinator: Oweiss, Karim G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.