Improving treatments for patients with acute ischemic stroke.
Official title: The University of Iowa Stroke Preclinical Assessment Network to Support Translational Studies for Acute Cerebroprotection
Funded at University of Iowa · NIH-10994128 · Data updated 2026-11-12
This study is looking for ways to better protect the brain during and after a stroke, and it's for people who have just experienced an acute ischemic stroke.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Iowa NIH-funded |
| Lab location | 1 site (Iowa City, United States) |
| Project start | December 15, 2022 |
| Project end | November 30, 2025 |
| Funding year | 2025 |
| Award (this year) | $544,713 |
| NIH project number | 5U01NS130587-03 |
| Project ID | NIH-10994128 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have recently experienced an acute ischemic stroke.
✕Less likely to help
Patients who have not had a stroke or those with chronic neurological conditions may not benefit from this research.
What this research studies
This research focuses on enhancing cerebroprotection strategies for patients experiencing acute ischemic stroke. The University of Iowa is part of a national network that conducts rigorous studies to evaluate new therapies aimed at protecting the brain during and after a stroke. By employing a clinical trial-like methodology, including randomization and blinded interventions, the research aims to produce reliable data that can inform future treatments. The team also considers factors like sex and existing health conditions to ensure the findings are applicable to a diverse patient population.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options that better protect the brain during acute ischemic strokes.
How similar studies have gone: Previous research in cerebroprotection has shown promise, indicating that this approach could lead to significant advancements in stroke treatment.
Where this research is happening
-
University of Iowa
Iowa City, United States Active
Researchers
- Principal investigator: Leira, Enrique Carlos — University of Iowa
- Study coordinator: Leira, Enrique Carlos
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.