Improving treatments for herpes simplex virus infections
Official title: Optimizing the Generation of Monoclonal Antibodies for Prevention and Treatment of HSV Disease
Funded at Albert Einstein College of Medicine · NIH-11080865 · Data updated 2026-11-12
This study is exploring new ways to help people with herpes by creating a special vaccine and antibodies that can boost the immune system to fight off the virus better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project start | June 6, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $594,071 |
| NIH project number | 5R01AI177673-03 |
| Project ID | NIH-11080865 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research would include individuals at risk for or currently infected with herpes simplex virus.
✕Less likely to help
Patients who are not infected with herpes simplex virus or those who have already developed effective immunity may not benefit from this research.
What this research studies
This research focuses on developing effective monoclonal antibodies and a novel vaccine to prevent and treat herpes simplex virus (HSV) infections. The approach involves a unique vaccine strain that has shown promise in protecting mice from HSV-1 and HSV-2. The study aims to understand how certain antibodies can activate immune responses to combat the virus, potentially leading to new therapies for patients suffering from HSV. By isolating specific antibodies that can effectively target the virus, the research seeks to enhance the body's ability to fight off infections.
Why it matters
Potential benefit: If successful, this research could lead to new treatments and preventive measures for herpes simplex virus infections, improving patient outcomes.
How similar studies have gone: Previous research has shown promise in developing antibody-based therapies for viral infections, suggesting potential for success in this novel approach.
Where this research is happening
-
Albert Einstein College of Medicine
Bronx, United States Active
Researchers
- Principal investigator: Herold, Betsy C. — Albert Einstein College of Medicine
- Study coordinator: Herold, Betsy C.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.