Improving treatments for childhood cystic kidney diseases

UAB Childhood Cystic Kidney Disease Core Center (UAB-CCKDCC)

NIH-funded research University of Alabama at Birmingham · NIH-10884920

This study is all about finding better ways to understand and treat kidney diseases in kids by looking at how certain proteins affect the disease and testing new treatments using patient samples and models.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Alabama at Birmingham NIH-funded
Lab location1 site (Birmingham, United States)
Project IDNIH-10884920 on NIH RePORTER

What this research studies

This research focuses on advancing the understanding and treatment of childhood cystic kidney diseases by collaborating with the PKD Consortium. A multidisciplinary team will work to eliminate barriers in research and develop innovative treatment strategies. The project aims to analyze how defects in specific proteins contribute to kidney disease progression and will provide access to clinical data and biomaterials from affected patients. Additionally, it will create patient-relevant cell and animal models to test potential therapies and improve disease management.

Who could benefit from this research

Good fit: Ideal candidates for this research include children diagnosed with autosomal recessive polycystic kidney disease or related cystic kidney disorders.

Not a fit: Patients with non-cystic kidney diseases or those who do not have a genetic predisposition to cystic kidney disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments and improved outcomes for children suffering from cystic kidney diseases.

How similar studies have performed: Previous research has shown promise in similar approaches to understanding and treating cystic kidney diseases, indicating a potential for success in this area.

Where this research is happening

Birmingham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Autosomal Recessive Medullary Cystic DiseaseAutosomal Recessive Polycystic Kidney Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.