Improving treatments for brain aneurysms
Improving outcomes in endovascular treatment of intracranial aneurysms: Combining additive manufacturing, in-silico modeling, and shape memory polymers
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA RIVERSIDE · NIH-10888375
This project aims to create new, personalized devices to better treat brain aneurysms and prevent serious complications like bleeding in the brain.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA RIVERSIDE (nih funded) |
| Locations | 1 site (RIVERSIDE, UNITED STATES) |
| Trial ID | NIH-10888375 on ClinicalTrials.gov |
What this research studies
Brain aneurysms can lead to a devastating condition called subarachnoid hemorrhage (SAH) if they rupture, which often causes severe brain damage or even death. While current treatments like coil embolization are common, they sometimes don't fully close the aneurysm, especially for complex shapes, leading to a high chance of the aneurysm returning. Our goal is to develop custom-made devices using advanced 3D printing and computer modeling to fit each patient's aneurysm perfectly. We hope these new devices will provide a more lasting and complete solution, reducing the risk of future problems.
Who could benefit from this research
Good fit: This research is most relevant to patients diagnosed with intracranial aneurysms, particularly those with wide-necked or complex aneurysm shapes that are challenging to treat with current methods.
Not a fit: Patients without intracranial aneurysms or those with conditions unrelated to acquired brain injury would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to more effective and durable treatments for intracranial aneurysms, significantly reducing recurrence rates and improving patient outcomes.
How similar studies have performed: This proposal builds upon existing preliminary data, but the specific combination of additive manufacturing, in-silico modeling, and shape memory polymers for personalized embolic devices represents a novel approach.
Where this research is happening
RIVERSIDE, UNITED STATES
- UNIVERSITY OF CALIFORNIA RIVERSIDE — RIVERSIDE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LEE, CHUNG-HAO — UNIVERSITY OF CALIFORNIA RIVERSIDE
- Study coordinator: LEE, CHUNG-HAO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired brain injury