NIH-funded research R01 grant

Improving treatment timing for craniofacial conditions using advanced imaging techniques

Official title: Evidence-based optimization of treatment timing in the craniofacial complex

Funded at University of Missouri-Columbia · NIH-11129373 · Data updated 2026-11-12

This study is working on improving treatment for kids with facial differences by using advanced 3D imaging to create better growth models, helping doctors make more informed decisions about their care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Missouri-Columbia
NIH-funded
Lab location1 site (Columbia, United States)
Project startMay 1, 2025
Project endJanuary 31, 2030
Funding year2025
Award (this year)$606,296
NIH project number1R01DE033416-01A1
Project IDNIH-11129373 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children aged 0-11 years who are experiencing craniofacial growth issues or abnormalities.

Less likely to help

Patients outside the age range of 0-11 years or those without craniofacial conditions may not benefit from this research.

What this research studies

This research focuses on enhancing treatment strategies for children with craniofacial conditions by developing new growth models that utilize advanced 3D imaging technology. By analyzing a large dataset of 40,000 3D craniofacial images, the study aims to create more accurate growth standards that reflect the complexities of craniofacial development. This innovative approach seeks to replace outdated 2D models, allowing for better-informed clinical decisions and treatment timing. The research will leverage state-of-the-art cone-beam computed tomography (CBCT) to ensure that clinicians have access to the most reliable data for patient care.

Why it matters

Potential benefit: If successful, this research could lead to more effective and timely treatments for children with craniofacial abnormalities, improving their overall health outcomes.

How similar studies have gone: Previous research has shown promise in utilizing advanced imaging techniques for craniofacial analysis, indicating that this approach could lead to significant advancements in treatment.

Where this research is happening

  • University of Missouri-Columbia
    Columbia, United States
    Active

Researchers

  • Principal investigator: Sherwood, Richard J — University of Missouri-Columbia
  • Study coordinator: Sherwood, Richard J

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.