Improving treatment strategies for opioid use disorder.
Official title: CTN'S CLINICAL COORDINATING CENTER CONTRACT. CTN STUDY, OPTIMIZING RETENTION, DURATION AND DISCONTINUATION STRATEGIES FOR OPIOID USE DISORDER PHARMACOTHERAPY (CTN-0100). POP: 8/15/24 - 4/2/28
Funded at The Emmes Company, LLC · NIH-11220970 · Data updated 2026-11-12
This study is looking for ways to make treatment for people with opioid use disorder more effective, helping them stay in therapy longer and manage their medication better, so they can have a smoother recovery journey.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | The Emmes Company, LLC NIH-funded |
| Lab location | 1 site (Rockville, United States) |
| Project start | August 15, 2024 |
| Project end | April 2, 2028 |
| Funding year | 2024 |
| Award (this year) | $3,419,274 |
| NIH project number | 75N95024D00037-0-759502400003-1 |
| Project ID | NIH-11220970 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with opioid use disorder who are seeking treatment options.
✕Less likely to help
Patients who are not struggling with opioid use disorder or those who are not interested in pharmacotherapy may not benefit from this research.
What this research studies
This research focuses on enhancing the effectiveness of pharmacotherapy for individuals struggling with opioid use disorder. It aims to optimize strategies for retaining patients in treatment, determining the appropriate duration of therapy, and managing discontinuation of medication. By analyzing various treatment approaches, the research seeks to identify best practices that can lead to better patient outcomes and reduce the impact of opioid addiction. Patients may be involved in trials that test these new strategies to improve their recovery journey.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatment options for patients with opioid use disorder, improving their chances of recovery.
How similar studies have gone: Previous research under the HEAL initiative has shown promise in improving treatment strategies for opioid addiction, indicating that this approach is building on established findings.
Where this research is happening
-
The Emmes Company, LLC
Rockville, United States Active
Researchers
- Principal investigator: Jelstrom, Eve — The Emmes Company, LLC
- Study coordinator: Jelstrom, Eve
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.