Improving treatment strategies for opioid use disorder

OPTIMIZING RETENTION, DURATION&DISCONTINUATION STRATEGIES FOR OPIOID USE DISORDER PHARMACOTHERAPY (CTN-0100). 03/01/2020 - 08/15/2022. N01DA-19-2250.T

['FUNDING_OTHER'] · THE EMMES COMPANY, LLC · NIH-10667369

This study is looking for better ways to help people with opioid addiction stay in treatment and figure out the best times to continue or stop their medication, so they can have a more successful recovery.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorTHE EMMES COMPANY, LLC (nih funded)
Locations1 site (ROCKVILLE, UNITED STATES)
Trial IDNIH-10667369 on ClinicalTrials.gov

What this research studies

This research focuses on enhancing the effectiveness of pharmacotherapy for individuals struggling with opioid use disorder. It aims to identify optimal strategies for retaining patients in treatment, determining the appropriate duration of therapy, and understanding when to safely discontinue medication. By analyzing data and patient outcomes, the study seeks to provide evidence-based recommendations that can improve the overall management of opioid addiction. Patients may be involved in various phases of treatment and data collection to help refine these strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with opioid use disorder who are currently receiving or are eligible for pharmacotherapy.

Not a fit: Patients who are not struggling with opioid use disorder or those who are not seeking treatment for their addiction may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatment protocols for opioid use disorder, improving recovery rates and quality of life for patients.

How similar studies have performed: Previous research initiatives under the NIH HEAL initiative have shown promise in improving treatment outcomes for opioid use disorder, indicating a strong potential for success in this area.

Where this research is happening

ROCKVILLE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.