NIH-funded research NIH-funded research

Improving treatment strategies for opioid use disorder

Official title: OPTIMIZING RETENTION, DURATION&DISCONTINUATION STRATEGIES FOR OPIOID USE DISORDER PHARMACOTHERAPY (CTN-0100). 03/01/2020 - 08/15/2022. N01DA-19-2250.T

Funded at The Emmes Company, LLC · NIH-10667369 · Data updated 2026-11-12

This study is looking for better ways to help people with opioid addiction stay in treatment and figure out the best times to continue or stop their medication, so they can have a more successful recovery.

More Opioid Use Disorder research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionThe Emmes Company, LLC
NIH-funded
Lab location1 site (Rockville, United States)
Project startMarch 1, 2020
Project endFebruary 28, 2026
Funding year2022
Award (this year)$1,350,572
NIH project number75N95019D00013-P00002-759502000002-1
Project IDNIH-10667369 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with opioid use disorder who are currently receiving or are eligible for pharmacotherapy.

Less likely to help

Patients who are not struggling with opioid use disorder or those who are not seeking treatment for their addiction may not benefit from this research.

What this research studies

This research focuses on enhancing the effectiveness of pharmacotherapy for individuals struggling with opioid use disorder. It aims to identify optimal strategies for retaining patients in treatment, determining the appropriate duration of therapy, and understanding when to safely discontinue medication. By analyzing data and patient outcomes, the study seeks to provide evidence-based recommendations that can improve the overall management of opioid addiction. Patients may be involved in various phases of treatment and data collection to help refine these strategies.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatment protocols for opioid use disorder, improving recovery rates and quality of life for patients.

How similar studies have gone: Previous research initiatives under the NIH HEAL initiative have shown promise in improving treatment outcomes for opioid use disorder, indicating a strong potential for success in this area.

Where this research is happening

  • The Emmes Company, LLC
    Rockville, United States
    Active

Researchers

  • Principal investigator: Vanveldhuisen, Paul — The Emmes Company, LLC
  • Study coordinator: Vanveldhuisen, Paul

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.