Improving treatment responses for pancreatic cancer

Pancreatic Cancer ARTNet Center

NIH-funded research University of Oklahoma Hlth Sciences Ctr · NIH-10926921

This study is looking into why pancreatic cancer patients sometimes don’t respond well to regular chemotherapy and aims to find new treatment options that could work better for them.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Oklahoma Hlth Sciences Ctr NIH-funded
Lab location1 site (Oklahoma City, United States)
Project IDNIH-10926921 on NIH RePORTER

What this research studies

This research focuses on understanding why pancreatic cancer patients often do not respond well to standard chemotherapy and how they develop resistance to these treatments. By investigating the signaling and metabolic changes in tumor cells and their surrounding environment, the research aims to identify new therapeutic combinations that can enhance treatment effectiveness. The project will also coordinate efforts with various cancer research networks to ensure comprehensive progress in tackling this challenging disease. Patients may benefit from novel therapies developed through this research that target the mechanisms of resistance.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with pancreatic cancer who are undergoing or have undergone chemotherapy.

Not a fit: Patients with pancreatic cancer who are not receiving chemotherapy or those with advanced disease not amenable to treatment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for pancreatic cancer, improving patient outcomes and survival rates.

How similar studies have performed: Previous research has shown promise in targeting cancer resistance mechanisms, suggesting that this approach could lead to significant advancements in treatment.

Where this research is happening

Oklahoma City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer CenterCancer PatientCancer Treatment
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.