NIH-funded research R01 grant

Improving treatment options for Trichomonas vaginalis infections in men and women.

Official title: Refining Trichomonas vaginalis treatment in women and men.

Funded at Tulane University of Louisiana · NIH-11061219 · Data updated 2026-11-12

This study is looking at a new single-dose medicine called secnidazole to see if it works better than the usual multi-dose treatment for Trichomonas vaginalis, a common infection that can cause health problems, and it's for both men and women who are dealing with this issue.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionTulane University of Louisiana
NIH-funded
Lab location1 site (New Orleans, United States)
Project startApril 1, 2024
Project endFebruary 28, 2029
Funding year2025
Award (this year)$1,347,276
NIH project number5R01AI183266-02
Project IDNIH-11061219 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals diagnosed with Trichomonas vaginalis, particularly those who have not responded well to existing treatments.

Less likely to help

Patients who do not have Trichomonas vaginalis or those who have already been successfully treated with current therapies may not benefit from this research.

What this research studies

This research focuses on enhancing the treatment of Trichomonas vaginalis, a common sexually transmitted infection that can lead to serious health issues. The study aims to compare the effectiveness of a new single-dose medication, secnidazole, against the current multi-dose treatment, metronidazole, which has shown high rates of treatment failure. By including both men and women in the trials, the research seeks to provide a more comprehensive understanding of effective treatments for this infection. Patients will be monitored for treatment outcomes and any potential side effects.

Why it matters

Potential benefit: If successful, this research could lead to more effective and convenient treatment options for Trichomonas vaginalis, reducing the incidence of treatment failures.

How similar studies have gone: Previous studies have shown promising results with similar treatment approaches, indicating potential for success in refining Trichomonas vaginalis treatment.

Where this research is happening

  • Tulane University of Louisiana
    New Orleans, United States
    Active

Researchers

  • Principal investigator: Kissinger, Patricia J — Tulane University of Louisiana
  • Study coordinator: Kissinger, Patricia J

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.