Improving treatment options for opioid use disorder
Design and analysis advances to improve generalizability of clinical trials for treating opioid use disorder
This study is looking at ways to make medications for opioid use disorder work better in real life by understanding how different personal factors affect treatment, so that more people can stay engaged in their recovery and reduce the risk of overdose.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10863916 on NIH RePORTER |
What this research studies
This research focuses on enhancing the effectiveness of medications for opioid use disorder (OUD) by addressing the gap between clinical trials and real-world applications. It aims to develop new design and analytic methods to ensure that clinical trials better reflect the diverse characteristics of patients in everyday settings. By understanding how various factors, such as psychiatric conditions and treatment history, influence treatment outcomes, the research seeks to improve long-term engagement in medication-assisted treatments. This could lead to more effective strategies for preventing overdose and improving recovery rates among individuals with OUD.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals aged 21 and older who are experiencing opioid use disorder and may benefit from medication-assisted treatment.
Not a fit: Patients who are not struggling with opioid use disorder or who are under 21 years old may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for individuals struggling with opioid use disorder.
How similar studies have performed: Other research has shown that improving the generalizability of clinical trials can lead to better treatment outcomes, making this approach promising and relevant.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Rudolph, Kara Elizabeth — Columbia University Health Sciences
- Study coordinator: Rudolph, Kara Elizabeth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.