NIH-funded research R01 grant

Improving treatment for voice tremors in people with essential tremor

Official title: ADVANCING THALAMIC NEUROSTIMULATION FOR SUPPRESING ESSENTIAL VOICE TREMOR

Funded at University of Florida · NIH-10999473 · Data updated 2026-11-12

This study is looking at how deep brain stimulation can help people with essential voice tremor feel better and communicate more easily by finding the best spot in the brain to target for treatment.

More Tremor research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Florida
NIH-funded
Lab location1 site (Gainesville, United States)
Project startDecember 11, 2023
Project endNovember 30, 2028
Funding year2025
Award (this year)$321,091
NIH project number5R01NS131342-02
Project IDNIH-10999473 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with essential tremor who experience significant voice tremors.

Less likely to help

Patients with essential tremor who do not experience voice tremors may not benefit from this research.

What this research studies

This research investigates the use of deep brain stimulation (DBS) to alleviate essential voice tremor (EVT), a condition affecting many individuals with essential tremor. The study aims to identify the optimal location in the thalamus for neurostimulation to effectively reduce both voice and upper limb tremors. By analyzing a large group of patients, the researchers will quantify changes in voice tremor and assess the effectiveness of DBS in improving communication and quality of life. This approach seeks to provide a more effective treatment option for those suffering from EVT.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment options for patients suffering from essential voice tremor, enhancing their ability to communicate.

How similar studies have gone: Previous studies have shown promising results with deep brain stimulation for upper limb tremors, but this specific application for voice tremor is still being explored.

Where this research is happening

  • University of Florida
    Gainesville, United States
    Active

Researchers

  • Principal investigator: Christou, Evangelos a — University of Florida
  • Study coordinator: Christou, Evangelos a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.