Improving treatment for repetitive negative thinking through attention and cognitive control.

Targeting Attentional and Cognitive Control to Enhance the Transdiagnostic Treatment of Repetitive Negative Thinking

NIH-funded research Massachusetts General Hospital · NIH-10821371

This study is looking for ways to help people who struggle with repetitive negative thoughts, like worries that stick around even after therapy, by testing a new treatment that focuses on improving how they pay attention and manage their feelings.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10821371 on NIH RePORTER

What this research studies

This research focuses on enhancing treatment for individuals experiencing repetitive negative thinking (RNT), which includes mental rituals and worries that often persist after cognitive behavioral therapy (CBT). The study aims to improve attention regulation skills through a new intervention called Emotion Regulation Therapy-Attention Regulation (ERT-AR). By comparing this approach to supportive psychotherapy, the research will measure improvements in cognitive control using various methods, including eye tracking and reaction time assessments. The goal is to identify effective strategies to help patients better manage their thoughts and emotions.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with affective disorders who experience repetitive negative thinking and have not responded adequately to traditional cognitive behavioral therapy.

Not a fit: Patients who do not experience repetitive negative thinking or those with conditions unrelated to affective disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for patients struggling with repetitive negative thinking, ultimately improving their mental health outcomes.

How similar studies have performed: Previous research has shown promise in enhancing cognitive control strategies for improving mental health outcomes, suggesting that this approach may yield beneficial results.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.