Improving treatment for PTSD and depression by focusing on how people process stressful events

Treatment of Stress-Related Psychopathology: Targeting Maladaptive and Adaptive Event Processing

NIH-funded research Case Western Reserve University · NIH-10928080

This study is exploring new treatments for PTSD and depression by looking at how people handle stressful experiences, with the goal of creating better therapies that help you cope positively and stick with your treatment.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionCase Western Reserve University NIH-funded
Lab location1 site (Cleveland, United States)
Project IDNIH-10928080 on NIH RePORTER

What this research studies

This research investigates new ways to treat posttraumatic stress disorder (PTSD) and depression by understanding how individuals process stressful life events. It aims to develop more effective therapies that not only address the negative aspects of these conditions but also promote resilience and positive coping strategies. By focusing on both maladaptive and adaptive processes, the research seeks to reduce dropout rates and improve long-term outcomes for patients. The approach combines insights from various studies to create interventions that are tailored to the needs of individuals experiencing these mental health challenges.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with PTSD or depression, particularly those who have experienced significant stressors and have not responded well to traditional therapies.

Not a fit: Patients who do not have PTSD or depression, or those who are not affected by stress-related psychopathology, may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for PTSD and depression, reducing symptoms and improving quality of life for many patients.

How similar studies have performed: Previous research has shown promise in addressing similar issues by focusing on the interplay between maladaptive and adaptive processes in mental health treatment.

Where this research is happening

Cleveland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions DiseaseDisorder
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.