Improving treatment for psychosis in Alzheimer's disease

Accelerating Treatment Development for Psychosis in AD: MODEL-AD+P

['FUNDING_R01'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-11134530

This study is looking to find better ways to treat people with Alzheimer's who experience psychosis by understanding what makes their condition different and testing new medications that could help improve their symptoms.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded)
Locations1 site (PITTSBURGH, UNITED STATES)
Trial IDNIH-11134530 on ClinicalTrials.gov

What this research studies

This research focuses on understanding and developing better treatments for psychosis in individuals with Alzheimer's disease (AD). It aims to identify the biological differences between those with psychosis and those without, and to find effective medications that can address these differences. The study will also create models to test these new treatments, which could lead to improved outcomes for patients experiencing psychotic symptoms associated with AD.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease who also experience psychotic symptoms.

Not a fit: Patients with Alzheimer's disease who do not exhibit psychotic symptoms may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for psychosis in Alzheimer's patients, potentially slowing cognitive decline and improving quality of life.

How similar studies have performed: Previous research has shown promise in identifying biological markers and potential treatments for psychosis in Alzheimer's, indicating that this approach could lead to significant advancements.

Where this research is happening

PITTSBURGH, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Alzheimer disease dementia, Alzheimer syndrome

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.