Improving treatment for patients with peripheral artery disease using advanced imaging techniques
Official title: Advancing Endovascular PAD Treatment: Overcoming Critical Knowledge Gaps with MRI-histology
Funded at Methodist Hospital Research Institute · NIH-11118665 · Data updated 2026-11-12
This study is looking to improve treatment for people with peripheral artery disease (PAD) by creating a new way to choose the best candidates for a specific procedure, while also finding tools that can help protect blood vessels during treatment, all with the goal of helping patients feel better and need fewer follow-up treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Methodist Hospital Research Institute NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | July 1, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $719,088 |
| NIH project number | 5R01HL174587-02 |
| Project ID | NIH-11118665 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with peripheral artery disease who are considering or have been recommended for percutaneous vascular interventions.
✕Less likely to help
Patients with PAD who are not candidates for percutaneous vascular interventions or those with other severe comorbidities may not benefit from this research.
What this research studies
This research focuses on enhancing the treatment of peripheral artery disease (PAD), which can lead to severe complications like amputation. The study aims to develop a new scoring system using MRI and histology to better select patients who will benefit from percutaneous vascular interventions (PVI). Additionally, it seeks to identify devices that minimize damage to blood vessels during these procedures. By addressing critical knowledge gaps, the research hopes to improve patient outcomes and reduce the need for repeat interventions.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for PAD, reducing the risk of amputation and improving overall limb health.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques to improve patient selection and outcomes in vascular interventions, indicating that this approach could be beneficial.
Where this research is happening
-
Methodist Hospital Research Institute
Houston, United States Active
Researchers
- Principal investigator: Roy, Trisha — Methodist Hospital Research Institute
- Study coordinator: Roy, Trisha
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.