Improving treatment for painful breast infections in breastfeeding individuals

Improving treatment of lactation mastitis: leveraging claims data to fill evidence gaps

NIH-funded research Trustees of Indiana University · NIH-10952650

This study is looking at how well different antibiotics work for treating lactation mastitis, a painful condition that many breastfeeding people experience, and it also wants to see if there are differences in treatment based on race and ethnicity.

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionTrustees of Indiana University NIH-funded
Lab location1 site (Bloomington, United States)
Project IDNIH-10952650 on NIH RePORTER

What this research studies

This research investigates lactation mastitis, a painful condition affecting many breastfeeding individuals, by analyzing healthcare claims data to compare the effectiveness of different antibiotic treatments. The study aims to identify which antibiotics are most effective in preventing treatment failure and to document any disparities in treatment based on race and ethnicity. By constructing a large cohort of over 5,000 diagnosed cases, the research team will conduct detailed analyses to understand the impact of antibiotic choice on outcomes like abscess formation and hospital admissions. This approach combines expertise from infectious disease epidemiology and lactation care to fill critical gaps in current treatment guidelines.

Who could benefit from this research

Good fit: Ideal candidates for this research are breastfeeding individuals diagnosed with lactation mastitis.

Not a fit: Patients who are not breastfeeding or who do not have a diagnosis of lactation mastitis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment protocols for lactation mastitis, reducing pain and complications for breastfeeding individuals.

How similar studies have performed: Previous research has shown that analyzing claims data can effectively identify treatment disparities and improve clinical outcomes, suggesting this approach has potential for success.

Where this research is happening

Bloomington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.