Improving treatment for neurological disorders in Africa

Global Research Endeavors to Advance Treatment of Neurological Disorders in Africa (GREAT Neurology)

NIH-funded research University of Rochester · NIH-11074084

This study is looking into how to better understand and treat brain-related issues in children, especially those affected by conditions like cerebral malaria and neuro-HIV in Africa, while also helping young doctors learn more about research.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-11074084 on NIH RePORTER

What this research studies

This research focuses on understanding and treating neurological disorders that are prevalent in Africa, particularly in resource-limited settings. It aims to investigate conditions like cerebral malaria and neuro-HIV through various methodologies, including cohort studies and randomized controlled trials. The research will assess the impact of neuroinflammation and co-infections, such as SARS-CoV-2, on neurological outcomes in affected children. Additionally, it seeks to mentor young clinician scientists to enhance local research capacity.

Who could benefit from this research

Good fit: Ideal candidates for participation include children suffering from cerebral malaria and individuals affected by neuro-HIV in Africa.

Not a fit: Patients outside of Africa or those not suffering from neurological disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for neurological disorders in African populations.

How similar studies have performed: Previous research has shown promise in addressing neurological disorders in similar contexts, indicating that this approach could yield valuable insights.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.