Improving treatment for mothers and infants affected by opioid use

Improving Treatment Engagement and Adherence to Optimize Outcomes for Opioid-Exposed Mother-Infant Dyads

['FUNDING_OTHER'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10595095

This study is looking at how different medications can help mothers with opioid use disorder stay on track with their treatment and keep both themselves and their babies healthy during and after pregnancy, so they can find better ways to support them, especially after giving birth.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorMASSACHUSETTS GENERAL HOSPITAL (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-10595095 on ClinicalTrials.gov

What this research studies

This research focuses on enhancing treatment engagement and adherence for mothers with opioid use disorder (OUD) and their infants. It aims to understand how different types of pharmacotherapy, such as methadone or buprenorphine, affect maternal and infant health outcomes during and after pregnancy. By analyzing data and exploring personal experiences, the study seeks to develop effective interventions that support mothers in maintaining their treatment, especially during the postpartum period when the risk of relapse is high.

Who could benefit from this research

Good fit: Ideal candidates for this research are pregnant or postpartum women with opioid use disorder and their infants.

Not a fit: Patients who are not pregnant or postpartum, or those without opioid use disorder may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved health outcomes for mothers and their infants affected by opioid use.

How similar studies have performed: Previous research has shown mixed results in improving treatment adherence for pregnant women with opioid use disorder, indicating that this approach may offer new insights and strategies.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.