Improving treatment for mitral regurgitation using personalized imaging techniques

In-Vivo Patient-Specific Optimization of Transcatheter-Edge-to-Edge Repair in Mitral Regurgitation

NIH-funded research University of Texas at Austin · NIH-10934339

This study is working on a new way to use special imaging to better understand how your heart's mitral valve moves, which could help doctors choose the best treatment for your mitral regurgitation and improve your care.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of Texas at Austin NIH-funded
Lab location1 site (Austin, United States)
Project IDNIH-10934339 on NIH RePORTER

What this research studies

This research focuses on enhancing the treatment of mitral regurgitation, a serious heart condition where the mitral valve does not close properly, allowing blood to flow backward. The team is developing a noninvasive imaging method to assess the shape and movement of the mitral valve in real-time, which could help tailor treatment options like the MitraClip procedure to individual patients. By analyzing patient-specific data, the goal is to predict which patients will benefit most from specific interventions, ultimately improving outcomes. The approach combines advanced 3-D echocardiography and modeling techniques to create a more personalized treatment plan.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients diagnosed with mitral regurgitation who are considering treatment options like the MitraClip procedure.

Not a fit: Patients with mitral regurgitation who are not candidates for surgical intervention or those with other severe comorbidities may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized treatments for patients with mitral regurgitation, improving their quality of life and reducing complications.

How similar studies have performed: Previous research has shown promise in using personalized imaging techniques for cardiac conditions, indicating potential success for this novel approach.

Where this research is happening

Austin, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.