Improving treatment for injured vocal folds
Optimal Tissue Engineering Approach for Treating Injured Vocal Folds
This study is testing a new way to help people with vocal fold injuries heal better and improve their voice using special gels that can be injected, making the treatment easier and less invasive.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | North Carolina State University Raleigh NIH-funded |
| Lab location | 1 site (Raleigh, United States) |
| Project ID | NIH-10530598 on NIH RePORTER |
What this research studies
This research focuses on developing a new tissue engineering approach to treat injuries in the vocal folds, which are crucial for voice production. It aims to restore the natural structure and function of the vocal folds by using injectable extracellular matrix hydrogels, which can promote tissue healing and reduce scarring. The study will explore the use of these hydrogels, potentially combined with therapeutic cells, to enhance recovery and improve voice quality for patients suffering from vocal fold injuries. Patients may benefit from minimally invasive procedures that can be performed in an office setting.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing voice impairments or injuries to their vocal folds.
Not a fit: Patients with voice disorders not related to vocal fold injuries or those who do not respond to tissue engineering approaches may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for voice impairments, improving communication abilities for millions of affected individuals.
How similar studies have performed: Previous research has shown promising results using similar tissue engineering approaches for other types of injuries, suggesting potential success for this novel application.
Where this research is happening
Raleigh, United States
- North Carolina State University Raleigh — Raleigh, United States (Active)
Researchers
- Principal investigator: Freytes, Donald O — North Carolina State University Raleigh
- Study coordinator: Freytes, Donald O
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.