Improving treatment for breast cancer that has spread to the brain
Enhanced Viro-Immunotherapy for Breast Cancer Brain Metastasis
['FUNDING_R01'] · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · NIH-11131347
This study is looking for ways to make a promising new treatment for breast cancer that has spread to the brain work better, by helping your immune system fight the cancer more effectively.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-11131347 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing viro-immunotherapy for patients with breast cancer that has metastasized to the brain. It aims to improve the effectiveness of oncolytic herpes simplex virus therapy, which has shown promise but currently has limited success due to the tumor's immunosuppressive environment. By understanding how the tumor microenvironment affects the immune response, the researchers hope to develop strategies that can boost the body's ability to fight the cancer. Patients may be involved in trials that test new treatment approaches designed to improve outcomes for this challenging condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with breast cancer that has spread to the brain.
Not a fit: Patients with breast cancer that has not metastasized to the brain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for breast cancer brain metastasis, potentially improving survival rates and quality of life for patients.
How similar studies have performed: Previous research has shown promise with similar viro-immunotherapy approaches in other cancers, indicating potential for success in this area as well.
Where this research is happening
HOUSTON, UNITED STATES
- UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: YOO, JI YOUNG — UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
- Study coordinator: YOO, JI YOUNG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Breast Cancer, Breast Cancer Patient, Cancer Patient