Improving treatment for brain aneurysms using advanced manufacturing techniques
Improving outcomes in endovascular treatment of intracranial aneurysms: Combining additive manufacturing, in-silico modeling, and shape memory polymers
This study is looking at new ways to treat brain aneurysms by making custom devices that fit each person's unique anatomy, with the goal of improving safety and effectiveness compared to current treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Riverside NIH-funded |
| Lab location | 1 site (Riverside, United States) |
| Project ID | NIH-11055929 on NIH RePORTER |
What this research studies
This research focuses on enhancing the treatment of intracranial aneurysms, which can lead to severe neurological damage or death if they rupture. By utilizing advanced 3D printing technology and personalized design, the project aims to create custom embolic devices that can effectively occlude aneurysms while addressing the unique anatomical features of each patient. The study will also compare the effectiveness of these new devices against current treatment methods to ensure better outcomes for patients. The approach combines experimental techniques with biomechanical modeling to optimize device performance.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with unruptured intracranial aneurysms, particularly those with complex geometries or wide-necked aneurysms.
Not a fit: Patients with ruptured aneurysms or those who do not have suitable anatomical features for the new embolic devices may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the recurrence rates of aneurysms and improve long-term outcomes for patients with intracranial aneurysms.
How similar studies have performed: Previous research has shown promise in using 3D printing for medical devices, indicating potential success for this innovative approach.
Where this research is happening
Riverside, United States
- University of California Riverside — Riverside, United States (Active)
Researchers
- Principal investigator: Lee, Chung-Hao — University of California Riverside
- Study coordinator: Lee, Chung-Hao
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.