Improving treatment for bone health in kidney disease patients
Precision medicine approaches to renal osteodystrophy
This study is looking at how to improve bone health for people with chronic kidney disease by exploring specific markers in the body and how parathyroid hormone affects bones, so we can find better ways to prevent fractures and heart problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10889222 on NIH RePORTER |
What this research studies
This research focuses on renal osteodystrophy, a condition affecting bone quality and strength in patients with chronic kidney disease. It aims to develop precision medicine approaches to better understand and treat this disorder by investigating the roles of specific biomarkers and the impact of parathyroid hormone levels on bone health. The study will analyze how current treatment guidelines can be improved to reduce the risk of fractures and cardiovascular events in these patients. By utilizing advanced diagnostic techniques, the research seeks to provide more accurate assessments of bone turnover and tailor treatments accordingly.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with chronic kidney disease who are experiencing issues related to renal osteodystrophy.
Not a fit: Patients with acute kidney injury or those not diagnosed with chronic kidney disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments that significantly reduce bone fractures and improve overall bone health in patients with chronic kidney disease.
How similar studies have performed: Previous research has indicated that precision medicine approaches can lead to significant advancements in treatment outcomes for chronic conditions, suggesting potential success for this novel approach.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Nickolas, Thomas L. — Columbia University Health Sciences
- Study coordinator: Nickolas, Thomas L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.