Improving treatment for blood donors with high cholesterol
Official title: IMPLEMENTING MULTICOMPONENT INTERVENTIONS TO TREAT BLOOD DONORS WITH FAMILIAL HYPERCHOLESTEROLEMIA
Funded at Ut Southwestern Medical Center · NIH-11085084 · Data updated 2026-11-12
This study is looking to make it easier for blood donors with Familial Hypercholesterolemia (FH) to get the cholesterol-lowering medications they need, by finding out what challenges they face and testing new ways to help them access treatment better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project start | March 1, 2022 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $452,076 |
| NIH project number | 5R33HL161753-04 |
| Project ID | NIH-11085084 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are blood donors who have been diagnosed with Familial Hypercholesterolemia.
✕Less likely to help
Patients who do not donate blood or those without a diagnosis of Familial Hypercholesterolemia may not benefit from this research.
What this research studies
This research aims to enhance the treatment of blood donors diagnosed with Familial Hypercholesterolemia (FH), a genetic condition that leads to high cholesterol levels. The project will identify barriers to treatment and develop strategies to improve access to cholesterol-lowering medications for these individuals. By utilizing blood donation centers as a platform, the study will implement and evaluate a comprehensive approach to increase the effectiveness of treatment for FH. The research will involve interviews and trials to gather data and assess the impact of the new strategies.
Why it matters
Potential benefit: If successful, this research could significantly improve the management and treatment of high cholesterol in blood donors, leading to better health outcomes.
How similar studies have gone: Previous research has shown that implementing targeted interventions in healthcare settings can effectively improve treatment adherence, suggesting potential success for this approach.
Where this research is happening
-
Ut Southwestern Medical Center
Dallas, United States Active
Researchers
- Principal investigator: Khera, Amit — Ut Southwestern Medical Center
- Study coordinator: Khera, Amit
Related research
Other NIH-funded projects on the same topics.
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Using behavioral nudges to improve family screening for inherited high cholesterol
This project uses two patient-facing approaches based on behavioral economics to help people with familial hypercholesterolemia get their relatives screened for the condition.
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Improving Risk Stratification for Familial Hypercholesterolemia (FH)
A patient-facing look at a study that aims to better predict who with familial hypercholesterolemia is at highest risk for early heart disease.
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Nonviral CRISPR-Cas9 delivery to liver cells to treat familial hypercholesterolemia
A new approach uses nonviral methods to deliver CRISPR-Cas9 to liver cells and select edited cells with acetaminophen, aiming to permanently lower bad cholesterol in people with familial hypercholesterolemia.
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Implementing multi-component approaches to help blood donors with familial hypercholesterolemia(
A program to help people who donate blood and have familial hypercholesterolemia get the cholesterol-lowering treatment they need through a blood-donation center.
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Helping families find and treat inherited high cholesterol
This project tests a clinic-based program to help primary care doctors find and treat children and adults with inherited high cholesterol (familial hypercholesterolemia).
-
Familial hypercholesterolemia: closing gaps in prevention of heart disease
A new NIH grant is exploring why people with familial hypercholesterolemia often go undiagnosed or receive uneven care, with the goal of improving early detection and prevention of heart disease.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.