Improving treatment for bladder cancer through genetic profiling and immunotherapy
SPORE in Bladder Cancer
This study is looking at how changes in the genes of bladder cancer tumors and blood can help doctors create better, personalized treatment plans for patients, including using immunotherapy, to improve how well treatments work for each individual.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10453628 on NIH RePORTER |
What this research studies
This research focuses on advancing the treatment of bladder cancer by analyzing genetic changes in tumors and blood samples. By understanding how these genetic alterations affect drug sensitivity, the study aims to personalize treatment plans for patients. The project also explores the use of immunotherapy and seeks to identify biomarkers that predict how well patients will respond to various treatments. A multidisciplinary team is working together to uncover inherited genetic risks and develop strategies to overcome resistance to immunotherapy.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with bladder cancer who are seeking innovative treatment options.
Not a fit: Patients with non-malignant bladder conditions or those who do not have bladder cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for bladder cancer patients.
How similar studies have performed: Other research has shown promising results in using genetic profiling and immunotherapy for cancer treatment, indicating that this approach has potential for success.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: Bajorin, Dean F. — Sloan-Kettering Inst Can Research
- Study coordinator: Bajorin, Dean F.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.