Improving treatment for balance and walking issues in Parkinson's disease

Targeted Pathway Activation for PosturalInstability and Gait Disorder in Parkinson'sDisease

NIH-funded research University of Minnesota · NIH-10879071

This study is looking at new ways to improve deep brain stimulation for people with Parkinson's disease who struggle with walking and balance, using advanced imaging and models to find the best treatment options for better results.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Minnesota NIH-funded
Lab location1 site (Minneapolis, United States)
Project IDNIH-10879071 on NIH RePORTER

What this research studies

This research focuses on enhancing deep brain stimulation (DBS) techniques to better address postural instability and gait disorders in patients with Parkinson's disease. By utilizing advanced MRI imaging and patient-specific computational models, the study aims to identify and target specific neural pathways that are more effective for treating these symptoms. The approach seeks to optimize DBS settings to improve patient outcomes, particularly for those whose walking and balance issues are not adequately managed by current therapies.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's disease who experience significant postural instability and gait disorders.

Not a fit: Patients with Parkinson's disease who do not experience postural instability or gait disorders may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for balance and walking difficulties in Parkinson's disease patients.

How similar studies have performed: Previous research has shown promise in using targeted stimulation techniques for other Parkinson's symptoms, suggesting potential for success in this novel approach.

Where this research is happening

Minneapolis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.