Improving treatment for acute ischemic stroke using a new thrombolysis system
Commercialization Readiness Pilot for Flow Acceleration for Stroke Thrombolysis (FAST) System
['FUNDING_OTHER'] · UNANDUP, LLC · NIH-11073962
This study is testing a new way to give a medication called alteplase faster and safer to people who have had an acute ischemic stroke, with the hope of helping more patients get the treatment they need.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNANDUP, LLC (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-11073962 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the treatment of acute ischemic stroke (AIS) by developing a novel system that accelerates the delivery of alteplase, a medication used to dissolve blood clots. The study aims to address the limitations of current thrombolysis practices, which are often underutilized due to safety concerns and eligibility restrictions. By improving the effectiveness and safety of thrombolysis, the research seeks to expand treatment options for a larger number of AIS patients. The approach involves innovative technology designed to optimize the administration of the drug, potentially leading to better patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing acute ischemic stroke who are currently eligible for thrombolysis treatment.
Not a fit: Patients who have experienced mild strokes or wake-up strokes, which are typically contraindicated for thrombolysis, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve recovery rates and reduce disability for patients suffering from acute ischemic stroke.
How similar studies have performed: While there have been advancements in thrombolysis techniques, this specific approach is novel and has not been extensively tested in prior research.
Where this research is happening
SAINT LOUIS, UNITED STATES
- UNANDUP, LLC — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CREIGHTON, FRANCIS MILTON — UNANDUP, LLC
- Study coordinator: CREIGHTON, FRANCIS MILTON
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.