Improving treatment for achalasia using a new endoscopic technique
PREcision MEDicine In Achalasia--PREMEDIA
This study is looking at a new procedure called POEM to see how well it helps people with achalasia, a condition that makes swallowing difficult, and it will compare different techniques to find the best way to improve treatment for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10722321 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of a new endoscopic procedure called per oral endoscopic myotomy (POEM) for treating achalasia, a condition that disrupts normal swallowing due to esophageal muscle dysfunction. The study aims to understand how variations in the myotomy technique affect patient outcomes, including the length and depth of the incision. By comparing this approach to traditional treatments, the research seeks to provide insights that could enhance the safety and efficacy of achalasia management for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with achalasia who are experiencing difficulties with swallowing and have not found relief from existing treatments.
Not a fit: Patients with other esophageal disorders or those who have already undergone surgical interventions for achalasia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options for patients with achalasia, potentially reducing complications and enhancing quality of life.
How similar studies have performed: Previous research has shown promising results with the POEM technique, indicating its potential as a less invasive alternative to traditional surgical methods.
Where this research is happening
Chicago, United States
- Northwestern University at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Pandolfino, John E — Northwestern University at Chicago
- Study coordinator: Pandolfino, John E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.