Improving treatment for abdominal infections using biomarkers
Official title: Biomarker-Guided Antimicrobial optimization to reduce complications from intra-abdominal infections
Funded at Surgical Infection Society Foundation for Education and Research · NIH-10923676 · Data updated 2026-11-12
This study is looking at how we can make antibiotic treatment for belly infections better by using a simple blood test to see how serious the infection is, so we can give just the right amount of medicine for each person instead of using the same treatment for everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Surgical Infection Society Foundation for Education and Research NIH-funded |
| Lab location | 1 site (East Northport, United States) |
| Project start | July 18, 2024 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $165,000 |
| NIH project number | 1R34AI178842-01A1 |
| Project ID | NIH-10923676 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with intra-abdominal infections who require antimicrobial therapy.
✕Less likely to help
Patients with non-intra-abdominal infections or those who do not require antimicrobial treatment may not benefit from this research.
What this research studies
This research focuses on enhancing the treatment of intra-abdominal infections by using biomarkers to tailor antimicrobial therapy. It aims to identify the optimal duration of antibiotic treatment based on individual patient needs rather than a one-size-fits-all approach. By measuring serum C-reactive protein (CRP) levels, the study seeks to determine the severity of infections and adjust treatment accordingly, potentially reducing complications and improving patient outcomes. The research will involve monitoring CRP levels over time to guide therapy decisions.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment for patients with intra-abdominal infections, reducing complications and improving recovery times.
How similar studies have gone: Previous research has shown promise in using biomarkers like CRP for managing infections, indicating that this approach could be effective.
Where this research is happening
-
Surgical Infection Society Foundation for Education and Research
East Northport, United States Active
Researchers
- Principal investigator: Sawyer, Robert G — Surgical Infection Society Foundation for Education and Research
- Study coordinator: Sawyer, Robert G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.