Improving treatment for abdominal infections using biomarkers
Biomarker-Guided Antimicrobial optimization to reduce complications from intra-abdominal infections
This study is looking at how we can make antibiotic treatment for belly infections better by using a simple blood test to see how serious the infection is, so we can give just the right amount of medicine for each person instead of using the same treatment for everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Surgical Infection Society Foundation for Education and Research NIH-funded |
| Lab location | 1 site (East Northport, United States) |
| Project ID | NIH-10923676 on NIH RePORTER |
What this research studies
This research focuses on enhancing the treatment of intra-abdominal infections by using biomarkers to tailor antimicrobial therapy. It aims to identify the optimal duration of antibiotic treatment based on individual patient needs rather than a one-size-fits-all approach. By measuring serum C-reactive protein (CRP) levels, the study seeks to determine the severity of infections and adjust treatment accordingly, potentially reducing complications and improving patient outcomes. The research will involve monitoring CRP levels over time to guide therapy decisions.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with intra-abdominal infections who require antimicrobial therapy.
Not a fit: Patients with non-intra-abdominal infections or those who do not require antimicrobial treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment for patients with intra-abdominal infections, reducing complications and improving recovery times.
How similar studies have performed: Previous research has shown promise in using biomarkers like CRP for managing infections, indicating that this approach could be effective.
Where this research is happening
East Northport, United States
- Surgical Infection Society Foundation for Education and Research — East Northport, United States (Active)
Researchers
- Principal investigator: Sawyer, Robert G — Surgical Infection Society Foundation for Education and Research
- Study coordinator: Sawyer, Robert G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.