Improving treatment decisions for opioid use disorder
Official title: Patient-centered decision making to improve opioid use disorder treatment
Funded at Vanderbilt University Medical Center · NIH-10928201 · Data updated 2026-11-12
This study is looking to improve how people with opioid use disorder get treated by making sure their voices are heard in the process, especially for those who also have issues with stimulants, so they can work better with their doctors to stick to their treatment plans.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | September 30, 2023 |
| Project end | September 29, 2028 |
| Funding year | 2024 |
| Award (this year) | $144,032 |
| NIH project number | 5K08HS029695-02 |
| Project ID | NIH-10928201 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with opioid use disorder, particularly those who also have stimulant use disorder.
✕Less likely to help
Patients who do not have opioid use disorder or stimulant use disorder may not benefit from this research.
What this research studies
This research focuses on enhancing the treatment of opioid use disorder (OUD) by developing a patient-centered approach that incorporates patient-reported outcome measures (PROMs) into clinical decision-making. The goal is to create an intervention that helps patients and providers work together more effectively during treatment, particularly for those also struggling with stimulant use disorder. By testing this intervention in a simulated setting and a pilot clinical trial, the research aims to determine if it can improve adherence to treatment and overall decision-making. This approach addresses the urgent need for tailored therapies in managing complex cases of OUD.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment adherence and better outcomes for patients with opioid use disorder.
How similar studies have gone: Previous research has shown that patient-centered approaches can significantly improve treatment outcomes in various health conditions, suggesting potential success for this novel intervention.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Reese, Thomas J — Vanderbilt University Medical Center
- Study coordinator: Reese, Thomas J
Related research
Other NIH-funded projects on the same topics.
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Optimizing opioid treatment for people leaving prison
This project tests simple screening and a small diagnostic checklist to help identify opioid use disorder in prisoners and link them to medication for opioid use disorder (MOUD) when they’re released.
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Systems analysis to improve opioid use disorder care after jail release (SAIA-MOUD)
A program to help people with opioid use disorder get better, faster, and safer care after they leave jail.
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Precise epigenetic drugs for opioid addiction
A tiny, targeted drug approach is being developed to help people with opioid use disorder by rewriting the epigenetic signals in the brain to reduce cravings and relapse risk.
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Increasing Access to Medications for Opioid Use Disorder for Unhoused Montanans
This project helps unhoused people in Montana get life-saving medicines for opioid use disorder through clinics connected to syringe service programs, a nurse-led MOUD model, and peer support.
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Optimizing long-acting PrEP and opioid treatment for people in jails and prisons
This project tests a real-world approach to using long-acting PrEP and buprenorphine for HIV prevention and opioid treatment among incarcerated individuals and after release.
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Scaling up medications for opioid use disorder in residential treatment programs
This grant studies how to help residential treatment programs provide medications for opioid use disorder to reduce overdoses after discharge, focusing on real-world settings and policies.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.