Improving treatment assessment for opioid use disorder using advanced data methods

Federated learning methods for heterogeneous and distributed Medicaid data

NIH-funded research University of Pittsburgh at Pittsburgh · NIH-10811726

This study is looking at how different treatments for opioid use disorder, especially buprenorphine, affect overdose deaths in people across different states, so that patients can get better treatment options and access to medications that fit their needs.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh NIH-funded
Lab location1 site (Pittsburgh, United States)
Project IDNIH-10811726 on NIH RePORTER

What this research studies

This research focuses on developing innovative federated learning techniques to analyze Medicaid data from multiple states, aiming to enhance the understanding of treatment effects for opioid use disorder (OUD). By utilizing a large-scale distributed research network, the project seeks to identify how different treatments, particularly buprenorphine, impact overdose mortality across diverse populations. The study addresses the challenges posed by varying state policies and aims to provide more precise health strategies tailored to individual needs. Patients may benefit from improved treatment options and better access to medications based on comprehensive data analysis.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals receiving Medicaid who are undergoing treatment for opioid use disorder.

Not a fit: Patients not enrolled in Medicaid or those not affected by opioid use disorder may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized treatment strategies for individuals with opioid use disorder.

How similar studies have performed: Previous research utilizing federated learning and large-scale Medicaid data has shown promise in improving treatment assessments, indicating a potential for success in this novel approach.

Where this research is happening

Pittsburgh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.