NIH-funded research NIH-funded research

Improving treatment and retention for opioid use disorder in primary care

Official title: Patient Reported Outcome Measures to Individualize Treatment And Improve ReteNtion (ReTAIN) program in primary care-based OUD treatment

Funded at University of Colorado Denver · NIH-10865966 · Data updated 2026-11-12

This study is looking to improve how we treat people with opioid use disorder by using feedback from patients to make their buprenorphine treatment more personalized and effective, especially in community health centers that help those most affected by the opioid crisis.

More Primary Care research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver
NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project startJuly 15, 2024
Project endJune 30, 2029
Funding year2024
Award (this year)$189,896
NIH project number1K23DA060358-01
Project IDNIH-10865966 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults aged 21 and older who are receiving treatment for opioid use disorder in primary care settings.

Less likely to help

Patients who are not seeking treatment for opioid use disorder or those who are not receiving care in primary care settings may not benefit from this research.

What this research studies

This research focuses on enhancing the treatment of opioid use disorder (OUD) in primary care settings by implementing a program that uses patient-reported outcome measures (PROMs). These measures help track how patients are responding to buprenorphine treatment, which is a common and effective therapy for OUD. By collecting and analyzing this data, the program aims to tailor treatments to individual patient needs and improve their overall experience and retention in care. The study will be conducted in Federally Qualified Health Centers, which serve underserved communities significantly affected by the opioid crisis.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment outcomes and higher retention rates for patients with opioid use disorder.

How similar studies have gone: Previous research has shown that using patient-reported outcome measures can enhance treatment effectiveness and patient engagement in various healthcare settings.

Where this research is happening

  • University of Colorado Denver
    Aurora, United States
    Active

Researchers

  • Principal investigator: Pytell, Jarratt — University of Colorado Denver
  • Study coordinator: Pytell, Jarratt

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.