Improving treatment adherence for sleep apnea in stroke patients during rehabilitation
Official title: Optimizing adherence to the treatment of sleep apnea among patients with strokeundergoing inpatient rehabilitation
Funded at University of Washington · NIH-11060937 · Data updated 2026-11-12
This study is looking to help stroke survivors in rehab use their CPAP machines more regularly to treat their sleep apnea by creating a special program just for them, making it easier and more engaging to stick with their treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | April 1, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $541,553 |
| NIH project number | 5R01HL164394-03 |
| Project ID | NIH-11060937 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are stroke survivors aged 21 and older who have been diagnosed with obstructive sleep apnea.
✕Less likely to help
Patients who do not have obstructive sleep apnea or are not recovering from a stroke may not benefit from this research.
What this research studies
This research focuses on enhancing adherence to continuous positive airway pressure (CPAP) treatment for obstructive sleep apnea (OSA) among stroke survivors undergoing inpatient rehabilitation. It aims to develop and test a tailored behavioral intervention that engages stroke patients to improve their CPAP usage. By refining existing behavioral strategies, the study seeks to address the unique challenges faced by stroke patients in adhering to OSA treatment. The intervention will be evaluated through a multicenter randomized controlled trial to determine its effectiveness in improving health outcomes.
Why it matters
Potential benefit: If successful, this research could significantly improve recovery and reduce the risk of recurrent strokes in patients with sleep apnea.
How similar studies have gone: Previous studies have shown that behavioral interventions can improve CPAP adherence in the general population, but this approach is novel for stroke patients.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Khot, Sandeep — University of Washington
- Study coordinator: Khot, Sandeep
Related research
Other NIH-funded projects on the same topics.
-
Improving WTC responder mental health with personalized sleep treatment for COMISA
Aimed at helping World Trade Center responders who have both insomnia and sleep apnea feel better by using a tailored combination of sleep therapies.
-
Central sleep apnea: how combined therapies could help you breathe better
This NIH grant explores how a combination of therapies, including a breathing device and a drug, might reduce central sleep apnea for people with heart failure or opioid use, by targeting the body’s breathing control system.
-
Mechanisms of sex-specific responses to sleep apnea therapies
A research project at NYU School of Medicine is exploring how men and women may respond differently to treatments for obstructive sleep apnea and related heart risk.
-
Deep learning to predict obstruction site and guide sleep apnea treatment
A patient-focused project uses snoring sounds and AI to predict where your airway collapses during sleep and to guide personalized treatments.
-
Personalized DISE-guided surgery for sleep apnea in children with Down syndrome
A personalized surgical approach guided by DISE sleep-endoscopy is being tested to better treat sleep apnea in children with Down syndrome who don’t always improve after standard surgery.
-
Biomarkers to understand obstructive sleep apnea using microRNAs
A study at the University of Pennsylvania will look for microRNA signs in the blood that reflect how bad sleep apnea is and how well CPAP therapy works for patients.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.