Improving treatment adherence for patients with bipolar disorder and substance use issues after hospital discharge
Official title: RCT to Improve Post-Hospital Treatment Adherence for Comorbid Substance Use and Bipolar Disorders
Funded at Butler Hospital (Providence, Ri) · NIH-10456650 · Data updated 2026-11-12
This study is looking for ways to help people with both bipolar disorder and substance use issues stick to their treatment after leaving the hospital, using a new support program that includes personal meetings and phone check-ins with family or friends over six months.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Butler Hospital (Providence, Ri) NIH-funded |
| Lab location | 1 site (Providence, United States) |
| Project start | September 10, 2019 |
| Project end | July 31, 2025 |
| Funding year | 2022 |
| Award (this year) | $601,769 |
| NIH project number | 5R01MH122870-04 |
| Project ID | NIH-10456650 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with both bipolar disorder and substance use disorders who are transitioning from psychiatric hospitalization to outpatient care.
✕Less likely to help
Patients who do not have a diagnosis of bipolar disorder or substance use disorders may not benefit from this research.
What this research studies
This research focuses on patients who have both bipolar disorder and substance use disorders, aiming to improve their adherence to treatment after they leave the hospital. It involves a novel psychosocial intervention called the Integrated Treatment Adherence Program (ITAP), which combines in-person engagement sessions and follow-up phone calls with support from family or significant others. The program is designed to address the heightened risk of relapse and nonadherence during the critical transition from hospital to outpatient care. By providing tailored support over six months, the research seeks to enhance treatment outcomes for these vulnerable patients.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment adherence and better overall health outcomes for patients with comorbid bipolar disorder and substance use disorders.
How similar studies have gone: Previous pilot data on the ITAP intervention have shown promising results, indicating that similar approaches may be effective in improving treatment adherence in this population.
Where this research is happening
-
Butler Hospital (Providence, Ri)
Providence, United States Active
Researchers
- Principal investigator: Gaudiano, Brandon a — Butler Hospital (Providence, Ri)
- Study coordinator: Gaudiano, Brandon a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.