Improving tracking and testing for sporadic behavioral frontotemporal dementia
Project 2
This project builds better ways to find what is causing symptoms in people with sporadic behavioral frontotemporal dementia and to follow their condition over time using clinical, biological, and remote tools.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-11198468 on NIH RePORTER |
What this research studies
This project focuses on people with sporadic behavioral variant frontotemporal dementia (s-bvFTD) to create models that link biological markers to how symptoms change over time. Researchers will adapt tools and biomarkers developed for genetic FTLD to work for sporadic cases where the cause is unknown. The team plans to combine clinical visits, biological samples, imaging, and remote assessments so patients can contribute data without frequent travel. The aim is to make diagnosis and tracking more accurate and to enable more precise, accessible clinical trials.
Who could benefit from this research
Good fit: People with a clinical diagnosis or suspected sporadic behavioral variant frontotemporal dementia who can provide clinical information, biological samples, and/or participate in remote monitoring are ideal candidates.
Not a fit: People whose symptoms are due to other dementias (for example, Alzheimer’s disease) or who have well-characterized familial FTLD may not directly benefit from this sporadic-focused project.
Why it matters
Potential benefit: If successful, patients could get earlier and more accurate diagnoses, easier remote monitoring, and more options to join targeted clinical trials.
How similar studies have performed: Work in familial FTLD has produced useful biomarkers and tools, but applying those approaches to sporadic bvFTD is relatively new and still being tested.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Boxer, Adam L. — Mayo Clinic Rochester
- Study coordinator: Boxer, Adam L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.