Improving tooth pulp healing and preventing infections
Official title: Angiogenic and anti-microbial supports for pulp regeneration
Funded at New Jersey Institute of Technology · NIH-11018532 · Data updated 2026-11-12
This study is exploring a new way to help heal damaged tooth nerves and prevent infections using a special gel that can be injected into the tooth, which could be great news for anyone who has had problems with their dental pulp.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New Jersey Institute of Technology NIH-funded |
| Lab location | 1 site (Newark, United States) |
| Project start | February 23, 2022 |
| Project end | January 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $587,065 |
| NIH project number | 5R01DE031812-04 |
| Project ID | NIH-11018532 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 21 and younger who have experienced trauma or infection affecting their dental pulp.
✕Less likely to help
Patients with fully devitalized teeth or those who are older than 21 may not benefit from this research.
What this research studies
This research focuses on developing a new material to help regenerate dental pulp tissue while preventing bacterial infections. The approach involves using self-assembling peptide hydrogels that can be injected into the tooth, providing both structural support and biological signals to promote healing. By targeting the dental pulp, which can become inflamed due to trauma or infection, this research aims to restore the tooth's vitality and function. Patients who have experienced dental pulp issues may benefit from this innovative treatment.
Why it matters
Potential benefit: If successful, this research could lead to improved healing of dental pulp and reduced pain for patients with pulp injuries or infections.
How similar studies have gone: Other research has shown promise in using similar biomaterials for tissue regeneration, indicating potential success for this approach.
Where this research is happening
-
New Jersey Institute of Technology
Newark, United States Active
Researchers
- Principal investigator: Kumar, Vivek — New Jersey Institute of Technology
- Study coordinator: Kumar, Vivek
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.