Improving tools to understand how cells develop and respond to diseases over time
Beyond Pseudotime: Enhanced Single-cell Genomics Tools for Understanding the Temporal Dynamics of Development and Disease
This study is looking at how individual cells grow and change over time, which could help us find better treatments for diseases and improve stem cell therapies for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project ID | NIH-10910060 on NIH RePORTER |
What this research studies
This research focuses on enhancing single-cell genomic technologies to better understand how cells develop and respond to various stimuli throughout their lifespan. By investigating the temporal dynamics of cellular differentiation and disease progression, the research aims to provide insights into how the genome regulates these processes from the earliest stages of development. Patients may benefit from new strategies in stem cell therapy and improved interventions for diseases as a result of this work.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with developmental disorders or diseases that involve cellular differentiation.
Not a fit: Patients with stable, non-progressive conditions that do not involve cellular differentiation may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating developmental disorders and diseases.
How similar studies have performed: Other research has shown success with similar genomic approaches, indicating potential for significant advancements in understanding cellular dynamics.
Where this research is happening
Tucson, United States
- University of Arizona — Tucson, United States (Active)
Researchers
- Principal investigator: Cusanovich, Darren a — University of Arizona
- Study coordinator: Cusanovich, Darren a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.