Improving tools for analyzing genetic data
Official title: Hypothesis Testing using Phylogenies for the 21st century
Funded at Temple Univ of the Commonwealth · NIH-11051139 · Data updated 2026-11-12
This study is working on better tools and software to help scientists understand genetic information more easily, so they can learn how evolution affects health and diseases.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Temple Univ of the Commonwealth NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | March 15, 2024 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $317,659 |
| NIH project number | 5R01GM151683-02 |
| Project ID | NIH-11051139 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals with genetic conditions or those interested in the genetic basis of diseases.
✕Less likely to help
Patients who do not have a genetic condition or are not involved in genetic research may not receive direct benefits from this research.
What this research studies
This research focuses on enhancing methods and software for analyzing genomic data, which has rapidly increased in volume over the past two decades. By developing and refining tools for comparative evolutionary analysis, the project aims to address the challenges faced by researchers in interpreting complex biological information. The work will leverage the popular HyPhy platform and its web application, Datamonkey, to provide accessible and efficient analysis options for scientists worldwide. Ultimately, this research seeks to improve the understanding of molecular evolution and its implications for health and disease.
Why it matters
Potential benefit: If successful, this research could lead to more effective tools for analyzing genetic data, benefiting patients through improved understanding of diseases and potential treatments.
How similar studies have gone: Previous research has shown success in developing analytical tools for genomic data, indicating that this approach has the potential for meaningful advancements.
Where this research is happening
-
Temple Univ of the Commonwealth
Philadelphia, United States Active
Researchers
- Principal investigator: Pond, Sergei L Kosakovsky — Temple Univ of the Commonwealth
- Study coordinator: Pond, Sergei L Kosakovsky
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.