Improving tools for analyzing genetic data

Hypothesis Testing using Phylogenies for the 21st century

['FUNDING_R01'] · TEMPLE UNIV OF THE COMMONWEALTH · NIH-11051139

This study is working on better tools and software to help scientists understand genetic information more easily, so they can learn how evolution affects health and diseases.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorTEMPLE UNIV OF THE COMMONWEALTH (nih funded)
Locations1 site (PHILADELPHIA, UNITED STATES)
Trial IDNIH-11051139 on ClinicalTrials.gov

What this research studies

This research focuses on enhancing methods and software for analyzing genomic data, which has rapidly increased in volume over the past two decades. By developing and refining tools for comparative evolutionary analysis, the project aims to address the challenges faced by researchers in interpreting complex biological information. The work will leverage the popular HyPhy platform and its web application, Datamonkey, to provide accessible and efficient analysis options for scientists worldwide. Ultimately, this research seeks to improve the understanding of molecular evolution and its implications for health and disease.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research include individuals with genetic conditions or those interested in the genetic basis of diseases.

Not a fit: Patients who do not have a genetic condition or are not involved in genetic research may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective tools for analyzing genetic data, benefiting patients through improved understanding of diseases and potential treatments.

How similar studies have performed: Previous research has shown success in developing analytical tools for genomic data, indicating that this approach has the potential for meaningful advancements.

Where this research is happening

PHILADELPHIA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.