Improving tools for analyzing and understanding DNA sequencing data

Methods for sequencing data analysis and archive-scale data science

['FUNDING_OTHER'] · JOHNS HOPKINS UNIVERSITY · NIH-11001936

This study is all about making it easier for scientists to understand DNA data, so they can find important information that helps with medical research and discoveries.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorJOHNS HOPKINS UNIVERSITY (nih funded)
Locations1 site (BALTIMORE, UNITED STATES)
Trial IDNIH-11001936 on ClinicalTrials.gov

What this research studies

This research focuses on developing and enhancing software tools that help biomedical researchers analyze and interpret DNA sequencing data more effectively. It aims to improve existing tools like Bowtie and Kraken 2, which are used for read alignment and metagenomics classification, respectively. The project will also create new systems that allow researchers to evaluate archived datasets for quality and relevance, enabling them to identify useful biological information without relying solely on metadata accuracy. By streamlining the process of data analysis, this research will facilitate better scientific discoveries and insights.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research include biomedical researchers and scientists working with DNA sequencing data.

Not a fit: Patients who are not involved in biomedical research or do not work with DNA sequencing data may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly enhance the ability of researchers to utilize archived DNA sequencing data, leading to improved understanding of biological processes and diseases.

How similar studies have performed: Previous research has shown success in developing similar bioinformatics tools, indicating a strong potential for this approach to yield valuable advancements.

Where this research is happening

BALTIMORE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.